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Incidence of Emergence Delirium in the Pediatric PACU: Prospective Observational Trial
Eva Klabusayová1,2, Tereza Musilová1,2, Dominik Fabián1,2
1Department of Paediatric Anaesthesia and Intensive Care Medicine, University Hospital Brno and Faculty of Medicine, Masaryk University, Kamenice 5, 62500 Brno, Czech Republic.
Insights
Emergence delirium (ED) in pediatric anesthesia can cause agitation and maladaptive behavior. A PAED score over 12 accurately identifies ED incidence in the post-anesthesia care unit.
Area of Science:
- Anesthesiology
- Pediatric Critical Care
Background:
- Emergence delirium (ED) is a common postoperative complication in pediatric anesthesia.
- It presents as psychomotor agitation and can lead to maladaptive behaviors lasting weeks.
- ED incidence varies widely (25-80%), particularly in children under 6.
Purpose of the Study:
- To determine the incidence of ED in pediatric patients (>1 month) post-general anesthesia.
- To evaluate the diagnostic accuracy of the Paediatric Anaesthesia Emergence Delirium (PAED) score, Watcha score, and Richmond Agitation-Sedation Scale (RASS).
Main Methods:
- Prospective study in the post-anesthesia care unit (PACU).
- Utilized PAED score, Watcha score, and RASS to assess ED.
- Analyzed incidence rates based on different score thresholds.
Main Results:
- PAED score with cutoff ≥10 points showed high incidence (89.0%), suggesting false positives.
- PAED score with cutoff >12 points indicated a more accurate ED incidence of 19.3%.
- Watcha and RASS scores reported lower incidences (18.8% and 18.1%, respectively).
Conclusions:
- A PAED score threshold >12 points is more accurate for diagnosing ED in pediatric patients.
- The RASS scale demonstrates good predictive value for ED, despite its primary use for sedation assessment.
Abstract:
Emergence delirium (ED) is a postoperative complication in pediatric anesthesia characterized by perception and psychomotor disorder and has a negative impact on morbidity in the form of maladaptive behavior, which can last weeks after anesthesia. Patients with developed ED present with psychomotor anxiety, agitation, and are at higher risk of unintentional extraction of an intravenous cannula, self-harm and nausea and vomiting. The described incidence of ED varies between 25−80%, with a higher prevalence among children younger than 6 years of age. We aimed to determine the incidence of ED in pediatric patients (>1 month) after general anesthesia in the post-anesthesia care unit (PACU), using Paediatric Anaesthesia Emergence Delirium (PAED) score, Watcha score and Richmond agitation and sedation scale (RASS). The incidence of ED was the highest in the PAED score with cutoff ≥10 points (89.0%, n = 1088). When using PAED score >12 points, ED incidence was 19.3% (n = 236). The lowest incidence was described by Watcha and RASS scores, 18.8% (n = 230) vs. 18.1% (n = 221), respectively. The threshold for PAED ≥10 points seems to give false-positive results, whereas the threshold >12 points is more accurate. RASS scale, although intended primarily for estimation of the depth of sedation, seems to have a good predictive value for ED.
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