Risk factors in schizophrenia: the Stony Brook High-Risk Project

Schizophrenia Bulletin
|January 1, 1987
PubMed

Insights

Children with a schizophrenic parent exhibit significant cognitive and social impairments. Environmental factors like family conflict predict psychopathology, highlighting the need for early intervention in high-risk families.

Area of Science:

  • Child and Adolescent Psychiatry
  • Developmental Psychology
  • Behavioral Genetics

Background:

  • Identifying early risk factors for psychopathology is crucial for timely intervention.
  • Family environment and parental mental health significantly influence child development.
  • Understanding precursor patterns can aid in predicting and preventing serious mental disorders.

Purpose of the Study:

  • To identify precursor patterns, environmental stressors, and protective factors for psychopathology.
  • To assess the differential predictive value of these factors in high-risk children.
  • To examine the long-term impact of parental mental illness on child adjustment.

Main Methods:

  • Longitudinal study of 544 children (aged 7-15) from families with parental schizophrenia, bipolar disorder, unipolar depression, or no parental illness.
  • Assessment of parental psychological functioning, family environment (conflict, parenting), and child adjustment.
  • Measurement of early signs of psychopathology, including cognitive slippage and attentional deficits.

Main Results:

  • Deviant family functioning (conflict, marital discord) was linked to poorer child adjustment.
  • Children with a schizophrenic parent displayed extensive cognitive, attentional, and social impairments.
  • At follow-up, 22.8% of children with a schizophrenic parent received a DSM-III diagnosis versus 9.6% of controls.

Conclusions:

  • Parental psychopathology and adverse family environments are significant risk factors for child psychopathology.
  • Early identification of cognitive, attentional, and social impairments is vital in high-risk populations.
  • Longitudinal data confirm increased risk for developing disorders in offspring of parents with severe mental illness.

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