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Menopause01:28

Menopause

233
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Bone Disorders01:29

Bone Disorders

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Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
458
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
571
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

529
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
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Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

2.1K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
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Updated: Aug 23, 2025

A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
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Metabolic Disorders in Menopause.

Hye Gyeong Jeong1,2, Hyuntae Park1

  • 1Department of Obstetrics and Gynecology, Korea University College of Medicine, 73 Inchon-ro, Seoul 02841, Korea.

Metabolites
|October 27, 2022
PubMed
Summary
This summary is machine-generated.

Menopause significantly elevates the risk of cardiometabolic diseases like obesity and metabolic syndrome (MetS). Understanding menopause

Keywords:
menopausemetabolic disordermetabolic syndromepostmenopause

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Area of Science:

  • Reproductive Endocrinology and Metabolism

Background:

  • Menopause marks a significant life stage, impacting women's health for up to one-third of their lives.
  • It substantially increases the risk of cardiometabolic diseases, including obesity, type 2 diabetes, cardiovascular disease, and metabolic-associated fatty liver disease (MAFLD).
  • Perimenopausal symptoms are often distressing, and associated factors can exacerbate the menopausal experience.

Purpose of the Study:

  • To review and confirm the association between menopause and metabolic diseases, with a focus on metabolic syndrome (MetS).
  • To explore the pathophysiology, definition, prevalence, diagnosis, management, and prevention strategies for these conditions.

Main Methods:

  • Literature review focusing on studies investigating menopause and cardiometabolic health.
  • Synthesis of existing research on the link between menopausal transition and metabolic disorders.

Main Results:

  • Menopause is strongly linked to an increased incidence of metabolic diseases.
  • Metabolic syndrome (MetS) is a key concern during and after menopause.
  • Factors influencing the menopausal experience also impact metabolic health.

Conclusions:

  • Menopause is a critical period for metabolic health, necessitating proactive management.
  • Controlling factors that worsen menopause symptoms may improve postmenopausal health outcomes.
  • Further research into prevention and management strategies is crucial.