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Surface-Enhanced Raman Spectroscopy Chips Based on Silver Coated Gold Nanostars
Miriam Parmigiani1, Benedetta Albini2, Giovanni Pellegrini2
1Department of Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.
Nanomaterials (Basel, Switzerland)
|October 27, 2022
Summary
Researchers enhanced surface-enhanced Raman scattering (SERS) substrates by coating gold nanostars with silver. This boosts sensitivity for detecting pollutants, achieving ultralow detection limits for molecules like norfloxacin.
Area of Science:
- Analytical Chemistry
- Materials Science
- Nanotechnology
Background:
- Surface-enhanced Raman scattering (SERS) is a powerful analytical technique.
- Developing stable, highly responsive SERS substrates for ultralow pollutant detection remains a challenge.
Purpose of the Study:
- To enhance the SERS response of gold nanostars (GNS) through silver coating.
- To develop efficient and reproducible SERS chips for pollutant detection.
Main Methods:
- Coating gold nanostars (GNS) with a silver layer of optimal thickness.
- Preparing glass-supported monolayers of GNS@Ag using alcoxyliane chemistry.
- Testing SERS chips for the detection of representative pollutant molecules.
Main Results:
- A 7-fold increase in SERS signals was achieved by coating GNS with silver.
- Efficient and reproducible SERS chips were successfully prepared.
- Norfloxacin was detected at concentrations as low as 3 ppb.
Conclusions:
- Silver-coated gold nanostars (GNS@Ag) significantly boost SERS signal intensity.
- The developed GNS@Ag SERS chips offer high sensitivity and reproducibility for pollutant detection.
- Achieved ultralow detection limits for norfloxacin demonstrate the potential of this SERS platform.
