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Rectal Cancer Presenting with Absceding Infection Due to Fusobacterium nucleatum

Sebastian Zundler1, Christian Mardin2, Simone Bertz3

  • 1Department of Medicine 1, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.

Pathogens (Basel, Switzerland)
|October 27, 2022
PubMed

Insights

Systemic infection with Fusobacterium nucleatum can indicate colorectal cancer. This case report emphasizes considering colon cancer in patients with Fusobacterium nucleatum infections and performing colonoscopy.

Area of Science:

  • Microbiology
  • Oncology
  • Gastroenterology

Background:

  • Intestinal microbiota, including Fusobacterium nucleatum, are implicated in colorectal cancer development.
  • Systemic infections caused by specific bacteria can serve as indicators for underlying diseases.

Observation:

  • A 47-year-old patient presented with endophthalmitis and liver abscess.
  • The causative agent identified was Fusobacterium nucleatum.

Findings:

  • The patient's systemic infection with Fusobacterium nucleatum led to the diagnosis of colorectal cancer.
  • Colorectal cancer was identified as the most probable primary source of the infection.

Implications:

  • Clinicians should consider colorectal cancer in patients presenting with systemic Fusobacterium nucleatum infections.
  • Diagnostic colonoscopy is recommended for patients with systemic Fusobacterium nucleatum infections to rule out colorectal cancer.
Keywords:
Fusobacterium nucleatumendophthalmitisliver abscessrectal cancer

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