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Carbon Dots for Killing Microorganisms: An Update since 2019
Fengming Lin1, Zihao Wang1, Fu-Gen Wu1
1State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, 2 Sipailou Road, Nanjing 210096, China.
Pharmaceuticals (Basel, Switzerland)
|October 27, 2022
Summary
Carbon dots (CDs) are effective antimicrobial nanomaterials offering alternatives to antibiotics for combating bacterial and fungal infections. This review highlights recent advancements in various types of antimicrobial CDs and their applications.
Area of Science:
- Materials Science
- Nanotechnology
- Biotechnology
Background:
- Antibiotic resistance and microbial infections necessitate novel antibacterial and antifungal agents.
- Carbon dots (CDs) show significant potential as antimicrobial nanomaterials, offering alternatives to conventional antibiotics.
Purpose of the Study:
- To review recent advancements in the development and application of carbon dots (CDs) for microbial inactivation.
- To provide a comprehensive overview of antimicrobial CDs, including their types, synthesis, and mechanisms.
Main Methods:
- Review of recent literature on carbon dots (CDs) for antimicrobial applications.
- Categorization of antimicrobial CDs into nitrogen-doped, metal-containing, antibiotic-conjugated, and photoresponsive types.
- Analysis of starting materials, synthesis routes, surface functionalization, and antimicrobial efficacy.
Main Results:
- Summarized recent achievements in utilizing CDs for microbial inactivation.
- Detailed four types of antimicrobial CDs: nitrogen-doped, metal-containing, antibiotic-conjugated, and photoresponsive.
- Highlighted emerging applications in medical and industrial fields.
Conclusions:
- Antimicrobial CDs represent a promising area for combating microbial infections.
- Further research into challenges and future directions is needed for optimizing antimicrobial CD development.
- This review offers insights for developing novel CDs with enhanced antimicrobial activities.
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