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Overlapping Presentations of HELLP Syndrome and COVID-19

Leila C Tou1, Andrew A Wang1, Taha A Siddiqui2

  • 1Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA.

European Journal of Case Reports in Internal Medicine
|October 27, 2022
PubMed

Insights

Diagnosing HELLP syndrome during COVID-19 is challenging due to similar symptoms. This case highlights the importance of considering HELLP syndrome in pregnant patients with COVID-19 for timely intervention.

Area of Science:

  • Obstetrics and Gynecology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Haemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is a critical condition in pregnancy.
  • Coronavirus disease 2019 (COVID-19) presents diagnostic challenges due to overlapping symptoms with HELLP syndrome.

Purpose of the Study:

  • To report a case of HELLP syndrome complicated by COVID-19 infection.
  • To emphasize the importance of differentiating between HELLP syndrome and COVID-19 in pregnant patients.

Main Methods:

  • Case report of a pregnant woman with concurrent COVID-19 and HELLP syndrome.
  • Clinical presentation, laboratory findings, and diagnostic considerations were analyzed.

Main Results:

  • The patient presented with symptoms consistent with both COVID-19 and HELLP syndrome.
  • Diagnosis of HELLP syndrome was confirmed post-delivery, with subsequent symptom resolution.

Conclusions:

  • COVID-19 and HELLP syndrome share overlapping clinical and laboratory features, necessitating careful evaluation.
  • Awareness of these similarities is crucial for prompt diagnosis and management to prevent maternal and fetal complications.
  • The temporal response to delivery can aid in differentiating HELLP syndrome from COVID-19.
Abstract

Keywords:
COVID-19HELLPSARS-CoV-2gestational hypertensionpreeclampsia

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