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Midterm Outcomes After Surgical Management for Mitral Valve Regurgitation in Infancy

Toshi Maeda1, Keiichi Fujiwara1, Kosuke Yoshizawa1

  • 1Department of Cardiovascular Surgery, 13863Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Hyogo, Japan.

World Journal for Pediatric & Congenital Heart Surgery
|October 27, 2022
PubMed

Insights

Mitral valve repair in infants with mitral regurgitation is safe and effective, showing good midterm results. This pediatric heart surgery offers a viable option for complex cases, improving patient outcomes.

Area of Science:

  • Pediatric Cardiology
  • Cardiac Surgery
  • Congenital Heart Disease

Background:

  • Mitral valve repair is the preferred treatment for pediatric mitral valve disease.
  • Infant mitral valve repair presents significant technical challenges due to complex lesions, limited surgical access, and tissue fragility.

Purpose of the Study:

  • To evaluate the midterm outcomes of mitral valve surgery for mitral regurgitation in infants.
  • To assess the safety and feasibility of mitral valve repair in this challenging patient population.

Main Methods:

  • Retrospective review of 18 infants (<12 months old) undergoing mitral valve surgery for mitral regurgitation.
  • Analysis of diverse etiologies including torn chordae, leaflet prolapse, hypoplasia, cleft, endocarditis, papillary muscle rupture, and hammock valve.
  • Follow-up data collected to assess reoperation rates, residual regurgitation, and survival.

Main Results:

  • No operative mortality; one late death.
  • Median follow-up of 7 years, 9 months.
  • 15 patients had mild or no mitral regurgitation post-repair; survival and reoperation-free rates at 10 years were 83.0%.

Conclusions:

  • Mitral valve repair for mitral regurgitation in infancy is a safe and feasible procedure.
  • Satisfactory midterm outcomes can be achieved, even in infants with severe preoperative conditions.
  • This approach offers a promising surgical option for pediatric mitral valve disease.
Abstract

Keywords:
CHDinfantmitral regurgitationmitral valvemitral valve repairvalve lesions

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