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Related Experiment Video

Updated: Aug 23, 2025

Author Spotlight: Investigating the Impact of Emotional Prosodies on Voice Recognition and Perception

Author Spotlight: Investigating the Impact of Emotional Prosodies on Voice Recognition and Perception

Published on: August 9, 2024

[A man with a low voice].

Yvo Smulders^1,2

¹Amsterdam UMC, afd. Interne Geneeskunde, Amsterdam.

Nederlands Tijdschrift Voor Geneeskunde

|October 27, 2022

Summary

Severe hypothyroidism can significantly alter a patient's voice due to vocal cord myxedema. Recovery from hypothyroidism often leads to a noticeable improvement in voice quality.

Area of Science:

Endocrinology
Otolaryngology

Background:

Hypothyroidism, a condition of insufficient thyroid hormone production, can manifest with various non-specific symptoms.
Vocal changes are not always recognized by patients as a symptom of hypothyroidism.

Observation:

A 57-year-old male patient presented with several non-specific complaints.
Severe hypothyroidism was diagnosed as the underlying cause of his symptoms.

Findings:

The patient's voice changes were attributed to vocal cord myxedema, a swelling of the vocal cords due to fluid accumulation caused by hypothyroidism.
Audio recordings demonstrated a profound alteration in voice quality during hypothyroidism and significant improvement post-treatment.

Implications:

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Highlights the importance of considering vocal changes as a potential symptom of hypothyroidism.

Underscores the impact of endocrine disorders on laryngeal function and voice production.

Emphasizes the diagnostic and therapeutic value of assessing voice changes in patients with suspected hypothyroidism.