Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Imaging Studies VII: Vascular Imaging

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Radial outer retina reflectivity (RORR) sign in LAMP2-associated retinopathy.

Acta ophthalmologica·2026

Same author

Clinical and Experimental Ophthalmology Goes Paperless in 2026.

Clinical & experimental ophthalmology·2025

Same author

HTRA1/lncRNA HTRA1-AS1 dominates in age-related macular degeneration reticular pseudodrusen genetic risk with no complement involvement.

Nature communications·2025

Same author

Internal Limiting Membrane Flap Versus Conventional Peeling for Idiopathic Full Thickness Macular Holes: A Registry Analysis of 2990 Eyes.

Clinical & experimental ophthalmology·2025

Same author

Inherited Retinal Disease or Age-Related Macular Degeneration: Predictive Value of Genetic Testing in Macular Disease With Atypical Atrophy.

Clinical & experimental ophthalmology·2025

Same author

Commentary on 'Genetic landscape of inherited retinal dystrophies in a Welsh tertiary referral centre'.

The British journal of ophthalmology·2025

Search research articles

Related Experiment Video

Updated: Aug 23, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Peripapillary hyperreflective ovoid mass-like structures: Multimodal imaging-A review.

Rachael C Heath Jeffery^1,2, Fred K Chen^1,2,3,4

¹Centre for Ophthalmology and Visual Science (incorporating Lions Eye Institute), The University of Western Australia, Nedlands, Western Australia, Australia.

Clinical & Experimental Ophthalmology

|October 27, 2022

Summary

This summary is machine-generated.

Peripapillary hyperreflective ovoid mass-like structures (PHOMS) are axonal herniations, not solely optic disc drusen. Their association with various optic nerve pathologies highlights their significance in neuro-ophthalmology.

Keywords:

optic disc drusen optic disc oedema optic nerve optical coherence tomography peripapillary hyperreflective ovoid mass-like structures

More Related Videos

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Published on: August 4, 2018

Related Experiment Videos

Last Updated: Aug 23, 2025

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy oSLO and Optical Coherence Tomography OCT

Published on: August 4, 2018

Area of Science:

Ophthalmology
Neuro-ophthalmology
Medical Imaging

Background:

Peripapillary hyperreflective ovoid mass-like structures (PHOMS) are characterized as herniations of distended axons.
Previously, PHOMS were often misidentified as buried optic disc drusen (ODD).
Advancements in enhanced depth imaging-optical coherence tomography (EDI-OCT) have improved visualization of the optic nerve head (ONH).

Purpose of the Study:

To differentiate PHOMS from other optic nerve pathologies.
To review the association of PHOMS with various neuro-ophthalmic conditions.
To identify knowledge gaps regarding PHOMS classification and prognosis.

Main Methods:

Review of current literature on PHOMS.
Analysis of imaging modalities for differential diagnosis.
Exploration of the relationship between PHOMS and optic nerve diseases.

Main Results:

PHOMS are distinct from buried ODD and associated with a wide range of optic nerve pathologies.
Frequent coexistence of PHOMS with ODD, papilledema, and anterior ischemic optic neuropathy observed.
Pathophysiology insights gained from association with conditions causing axoplasmic stasis.

Conclusions:

PHOMS represent a significant finding beyond buried ODD.
Understanding PHOMS' associations is crucial for neuro-ophthalmic diagnosis.
Further research is needed for PHOMS classification and prognosis.