Related Experiment Video
Updated: Oct 17, 2026

Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
FMT: What's Next? A Narrative Review of Fecal Microbiota Transplantation in Clostridioides difficile Infection and
Sohum A Patwa1, Christopher Ward2, Colleen R Kelly3
1Resident Physician, Department of Internal Medicine, Warren Alpert Medical School of Brown University, Providence, RI.
Abstract:
Fecal microbiota transplantation (FMT) is an increasingly employed treatment option for Clostridioides difficile infection (CDI), with growing data supporting its safety and effectiveness in patients with concurrent inflammatory bowel disease (IBD). Given that alterations in the gut microbiome are associated with both ulcerative colitis (UC) and Crohn's disease (CD), the use of FMT for the treatment of IBD itself is another area of active investigation. In this narrative review, we highlight the evidence for use of FMT in the treatment of CDI in patients with IBD, as well as for IBD alone, and provide insight into the future of microbiome therapeutics.
Related Concept Videos
Overview of Human Digestion
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Microbiota of the Large Intestine
Dysbiosis of the Gut Microbiota
Microbiota Modulation by Antibiotics
Inflammatory Bowel Disease III: Crohn's Disease

