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Draft Genome Sequence of Clinical Isolate USM039K of the Pathogenic Yeast Candida parapsilosis

Dina Yamin1, Wan Khairunnisa Wan Juhari1,2, NurWaliyuddin Hanis Zainal Abidin3

  • 1Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.

Microbiology Resource Announcements
|October 27, 2022
PubMed

Insights

We present the draft genome sequence of Candida parapsilosis USM039K, a clinical isolate from a catheter-related bloodstream infection. This genomic data aids in understanding this opportunistic fungal pathogen.

Area of Science:

  • Medical Mycology
  • Genomics
  • Infectious Diseases

Background:

  • Candida parapsilosis is a significant cause of opportunistic fungal infections, particularly bloodstream infections.
  • Catheter-related bloodstream infections (CRBSI) pose a serious threat in healthcare settings.
  • Understanding the genetic makeup of clinical isolates is crucial for developing targeted therapies.

Purpose of the Study:

  • To announce the draft genome sequence of a specific clinical isolate of Candida parapsilosis (USM039K).
  • To provide foundational genomic data for a strain involved in a catheter-related bloodstream infection.

Main Methods:

  • Whole-genome sequencing of the Candida parapsilosis clinical isolate USM039K.
  • Bioinformatic analysis to assemble the genome and identify key features.

Main Results:

  • The draft genome sequence of Candida parapsilosis USM039K has been generated.
  • The genome comprises 12,860,016 base pairs, organized into 188 scaffolds.
  • The G+C content is 38.65%, and 5,467 genes were identified.

Conclusions:

  • The availability of this draft genome sequence provides valuable genetic resources for Candida parapsilosis research.
  • This data can facilitate further studies into the virulence factors and antifungal resistance mechanisms of this opportunistic pathogen.

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