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Updated: Aug 14, 2026

3-D Imaging and Analysis of Neurons Infected In Vivo with Toxoplasma gondii
Published on: December 9, 2014
Parasite potpourri: Toxoplasma gondii lineage tracing in vivo
1Department of Neurology, Department of Immunobiology, BIO5 Institute, University of Arizona, Tucson, AZ, USA.
Abstract:
Using a CRISPR/Cas9-based method, Wincott et al. generated a stable, complex Toxoplasma gondii population composed of 96 barcoded clonal lineages. By tracking the population structure in vivo, they determine that - contrary to expectations - the pathway to infecting the brain is widely permissive for T. gondii.
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