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Published on: March 4, 2014
Laboratory prognostic factors for the long-term survival of multiple system atrophy
Jung Hwan Shin1, Han-Joon Kim2, Chan Young Lee3
1Department of Neurology, Seoul National University Hospital & Seoul National University College of Medicine, Seoul, South Korea.
Abstract:
To elucidate the biomarkers related to survival in multiple system atrophy(MSA), we analyzed the predictability of retrospectively collected blood markers for survival in 650 probable MSA. High absolute neutrophil count, red-cell distribution width, C-reactive protein, erythrocyte sedimentation rate, and low hemoglobin, protein, albumin, and creatinine were correlated with higher mortality in MSA. Systemic alteration in inflammation and nutritional status in the early stage are associated with higher mortality in MSA.
