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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Related Experiment Video

Updated: Aug 23, 2025

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
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Cold intolerance and associated factors: a population study.

Alireza Khabbazi1, Rojin Farzaneh2, Maryam Mahmoudi2

  • 1Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Imamreza Hospital, Flat 1, P.O Box 5166614756, Tabriz, Iran. dr.khabazi@gmail.com.

Scientific Reports
|October 27, 2022
PubMed
Summary

Cold intolerance, a condition causing discomfort upon cold exposure, affects 11.1% of the general population in Tabriz. This common issue is more prevalent in females and individuals with comorbidities.

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Area of Science:

  • Medical Science
  • Public Health

Background:

  • Cold intolerance involves symptoms like pain, numbness, and skin changes upon cold exposure.
  • It can significantly impact an individual's quality of life.

Purpose of the Study:

  • To determine the prevalence of cold intolerance in the general population of Tabriz.
  • To identify factors associated with cold intolerance.

Main Methods:

  • A cross-sectional study involving simple random sampling of adults (≥18 years) in Tabriz.
  • Telephone interviews were conducted, and the Cold Intolerance Symptom Severity (CISS) questionnaire was used with a cutoff of 50.
  • 322 individuals completed the survey.

Main Results:

  • Cold intolerance was reported by 11.1% (38 out of 322) of participants.
  • Cold intolerance was significantly more common in females and individuals with comorbidities.
  • Job quality was affected in 8.4% and job changes occurred in 1.9% of those with cold intolerance.

Conclusions:

  • Cold intolerance is a prevalent condition within the general population of Tabriz.
  • The study highlights the need to address cold intolerance and its associated factors.