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Glioblastoma Multiforme Survivor With Radiation-Induced Consequences: A Case Report
Christina M Hunt1, Virginia Thomas2, Julia Alexander3
1Orthopaedics, Alabama College of Osteopathic Medicine, Dothan, USA.
Cureus
|October 28, 2022
Summary
Aggressive treatment for glioblastoma multiforme, including surgery and radiation, can extend survival but carries risks like secondary meningiomas. Balancing extended life with quality of life is crucial for patients.
Area of Science:
- Neuro-oncology
- Radiation Oncology
Background:
- Glioblastoma multiforme is an aggressive brain tumor with a poor prognosis.
- Current treatments include surgery, radiation, and chemotherapy.
Observation:
- This case report details a patient with glioblastoma multiforme treated with surgery and radiation.
- The patient later developed a radiation-induced meningioma.
Findings:
- Despite treatment-related morbidities, the patient experienced prolonged survival.
- Young age at diagnosis may be a factor in extended survival.
Implications:
- Aggressive glioblastoma multiforme treatment requires careful risk-benefit discussion with patients.
- Potential long-term consequences include post-surgical changes, vascular dementia, strokes, and secondary meningiomas.
- Maintaining a high quality of life should be a primary goal in all treatment plans.
