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Updated: Aug 23, 2025

A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research
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Autism as emergent and transactional.

Jonathan Green1

  • 1Division of Psychology and Mental Health, Faculty of Biology Medicine and Health, Manchester Academic Health Sciences Centre, Royal Manchester Children's Hospital, University of Manchester, Manchester, United Kingdom.

Frontiers in Psychiatry
|October 28, 2022
PubMed
Summary

Autism

Area of Science:

  • Developmental neuroscience
  • Behavioral science
  • Genetics

Background:

  • Current autism understanding relies on categorical descriptions and essentialist biological theories.
  • High heritability led to a search for discrete biological markers, which has yielded limited success.
  • This has prompted a shift towards dimensional accounts of autism.

Purpose of the Study:

  • To propose and provide evidence for a transactional approach to understanding autism.
  • To view autistic states as emergent properties of neurodivergent individuals interacting with their environment.
  • To challenge essentialist views and integrate dimensional and categorical perspectives.

Main Methods:

  • Analysis of random allocation intervention trials in infancy and early childhood.
Keywords:
autismautism spectrum conditionsclinical trialsemergenceinterventionneurodivergenceneurodiversitytransaction

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  • Interventions focused on altering the quality of the social transactional environment.
  • Assessment of changes in dimensional autistic phenotype and categorical classification status.
  • Main Results:

    • Targeted environmental changes led to significant, predictable, and sustained alterations in the autistic phenotype.
    • One trial showed a reduction in later categorical classification status.
    • The prototypical autistic phenotype demonstrated malleability with environmental shifts.

    Conclusions:

    • Autistic phenotypes are emergent properties influenced by environmental interactions.
    • A transactional approach expands the concept of the phenotype and aligns with developmental science.
    • This perspective challenges essentialist theories and supports a social model of autism, reflecting lived experiences.