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Azacitidine-induced myopericarditis in acute myeloid leukemia
Mahmoud Ismayl1, Asmini Kc2, Abhishek Thandra3
1Department of Internal Medicine, Creighton University School of Medicine, Omaha, Nebraska.
Abstract:
Hypomethylating agents are commonly used in the treatment of myelodysplastic syndromes and are known to cause bone marrow suppression; however, cardiac complications are rare. We describe a patient who was diagnosed with acute myeloid leukemia and developed myopericarditis after receiving chemotherapy with azacitidine. Our case highlights the importance of a thorough history, including medication review, in patients with suspected myopericarditis. It also raises awareness about the potential cardiac side effects of azacitidine.
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