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Updated: Aug 23, 2025

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Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
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PFO Closure after Pulmonary Valve Intervention in Patients with Hypoxemia Due to Right-to-Left Intracardiac Shunt
Suhas Babu1,2, Zhihao Zhu1, Miguel Chavez3
1Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, Houston, Texas, US.
Methodist Debakey Cardiovascular Journal
|October 28, 2022
Abstract:
Four patients with pulmonary valve (PV) disease and patent foramen ovale (PFO) presented with dyspnea on exertion. Work-up revealed hypoxemia secondary to right-to-left intracardiac shunt. We demonstrate that correction of the primary culprit right heart overload lesion via PV replacement enabled safe PFO repair and resolution of hypoxemia.
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