Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Feedback Inhibition

Feedback Inhibition

Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!

Feedback Loops

Feedback Loops

In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.

Journal Bearings

Journal Bearings

Journal bearings are mechanical components that support and provide lateral stability to rotating shafts and axles. They are crucial in reducing friction, wear, and vibration in machinery such as engines, turbines, and pumps. The principle behind journal bearings is forming a thin lubricant film between the bearing surface and the rotating shaft, which minimizes direct contact and reduces frictional forces.
To better understand the concept of journal bearings, consider a rope winch with dry or...

Proofreading

Proofreading

Altruism

Altruism

Altruistic behaviors are “unselfish” behaviors—those that help another individual at the expense of the individual carrying out the behavior. Despite the negative consequences for the altruistic animal, these behaviors are thought to have evolved for several reasons.

Communication

Communication

Communication between two animals occurs when one animal transmits an information signal that causes a change in the animal that receives the information. Organisms communicate with one another in a host of different ways. Signals can be auditory, chemical, visual, tactile, or a combination of these. Communication is a critical behavioral adaptation that promotes survival, growth, and reproduction.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Primary intracranial sarcoma, DICER1-mutant: 5 cases highlighting variable clinical and molecular features.

Journal of neuropathology and experimental neurology·2026

Same author

Cubic Millimeter High Resolution 3D Inner-Volume GRASE (IV-GRASE) CEST MRI Using T<sub>1</sub>-Integrated Variable Density CAIPI Sampling With Temporal Random Walk: A Feasibility Study.

Magnetic resonance in medicine·2026

Same author

Region-specific human brain organoids reveal synaptic and cell state drivers of glioblastoma invasion.

bioRxiv : the preprint server for biology·2025

Same author

Telecare enhances the retention of patients with inflammatory bowel disease within a tertiary care inflammatory bowel disease center.

Journal of telemedicine and telecare·2025

Same author

Pulsed Field Ablation for Persistent Atrial Fibrillation: 1-Year Results of ADVANTAGE AF.

Journal of the American College of Cardiology·2025

Same author

Multiple meningiomas of different variants in a single patient: illustrative cases.

Journal of neurosurgery. Case lessons·2025

Search research articles

Related Experiment Video

Updated: Aug 23, 2025

Perspectives on Neuroscience

Perspectives on Neuroscience

Published on: July 31, 2007

Letter to the Editor.

Abigail Goodman¹, Jose Velazquez-Vega², Jeffrey Olson³

¹Carolinas Healthcare System, Charlotte, United States.

Journal of Neuro-Oncology

|October 28, 2022

Summary

This summary is machine-generated.

The terminology for progressive glioblastoma in adult neuro-oncology guidelines has been updated to "glioblastoma, IDH-wildtype WHO grade 4" to align with the 2021 World Health Organization classification.

More Related Videos

Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases

Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases

Published on: November 8, 2024

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Published on: March 30, 2021

Related Experiment Videos

Last Updated: Aug 23, 2025

Perspectives on Neuroscience

Perspectives on Neuroscience

Published on: July 31, 2007

Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases

Author Spotlight: Dermatopathology and the Treatment of Sexually Transmitted Diseases

Published on: November 8, 2024

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Focal Laser Ablation of Prostate Cancer: An Office Procedure

Published on: March 30, 2021

Area of Science:

Neuro-oncology
Neuropathology
Central Nervous System Tumors

Background:

The recent Congress of Neurological Surgeons guidelines for progressive glioblastoma used 2016 World Health Organization (WHO) terminology.
Updating the terminology is crucial for aligning with current scientific parlance and classification systems.

Discussion:

The 2021 WHO Classification of Tumors of the Central Nervous System introduces updated terminology for CNS tumors.
This update necessitates a review of existing guidelines to ensure consistency with the latest diagnostic criteria.

Key Insights:

The term "glioblastoma, IDH-wildtype WHO grade 4" is the most accurate representation of tumors previously termed "glioblastoma" under the 2016 WHO classification.
This specific terminology was selected to replace "glioblastoma" in the updated neuropathology guidelines.

Outlook:

Adoption of the "glioblastoma, IDH-wildtype WHO grade 4" terminology will enhance clarity and precision in clinical practice and research.
Future neuro-oncology guidelines should consistently adopt the 2021 WHO classification for improved standardization.