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Updated: Aug 23, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
High-Resolution Computed Tomography of Fibrotic Interstitial Lung Disease
Karen Rodriguez1, Christian L Ashby2, Valeria R Varela2
1Division of Thoracic Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts.
High-resolution computed tomography (HRCT) offers detailed lung imaging for fibrotic interstitial lung diseases. HRCT patterns, combined with clinical data, aid diagnosis, prognosis, and treatment monitoring.
Area of Science:
- Radiology
- Pulmonary Medicine
- Medical Imaging
Background:
- Radiography is the initial imaging modality for pulmonary disease.
- High-resolution computed tomography (HRCT) provides detailed lung parenchyma and interstitium assessment.
- HRCT differentiates normal anatomy from abnormal findings.
Purpose of the Study:
- Describe HRCT technique for lung evaluation.
- Illustrate normal and abnormal lung appearance on HRCT.
- Detail HRCT patterns in common fibrotic interstitial lung diseases.
Main Methods:
- Utilizing HRCT for detailed lung parenchyma and interstitium assessment.
- Characterizing HRCT features such as reticulation, traction bronchiectasis, honeycombing, architectural distortion, and volume loss.
- Analyzing the distribution and patterns of these features.
Main Results:
- HRCT reveals specific patterns indicative of fibrotic interstitial lung diseases.
- These patterns include reticulation, traction bronchiectasis, honeycombing, architectural distortion, and volume loss.
- CT patterns and their progression are crucial for diagnosis and management.
Conclusions:
- HRCT is essential for diagnosing and monitoring fibrotic interstitial lung diseases.
- Combining HRCT patterns with clinical, serologic, and pathologic data facilitates diagnosis.
- Serial HRCT examinations track disease progression, treatment response, and prognosis.
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