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Related Experiment Video

Updated: Aug 23, 2025

Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
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Pectus excavatum in motion: dynamic evaluation using real-time MRI.

Daniel Gräfe1, Martin Lacher2, Illya Martynov2

  • 1Department of Pediatric Radiology, University Hospital, Leipzig, Germany. daniel.graefe@medizin.uni-leipzig.de.

European Radiology
|October 28, 2022
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Summary
This summary is machine-generated.

Thoracic indices for pectus excavatum are breathing phase dependent. Real-time MRI shows quiet expiration is best for reliable assessment of these chest wall morphologic indices.

Keywords:
Funnel chestMagnetic resonance imagingThoracic wall

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Area of Science:

  • Medical imaging
  • Thoracic surgery
  • Pediatric cardiology

Background:

  • Standardized breathing phases are crucial for accurate thoracic index determination in pectus excavatum.
  • Current methods lack standardization, potentially affecting diagnostic reliability.

Purpose of the Study:

  • To identify the optimal breathing phase for reliable assessment of thoracic indices in pectus excavatum using real-time MRI.
  • To dynamically evaluate chest wall motion and its impact on morphologic indices.

Main Methods:

  • Prospective study utilizing 3T real-time MRI in 56 pectus excavatum patients.
  • Morphologic indices (Haller, correction, asymmetry, eccentricity) measured during free, quiet, and forced breathing.
  • Statistical analysis (Wilcoxon signed-rank test) and chest wall motion analysis.

Main Results:

  • Thoracic indices varied significantly with breathing phase, particularly between peak inspiration and expiration.
  • No significant index variation was observed during different expiratory phases (p > .05).
  • Real-time MRI identified three distinct chest wall movement patterns.

Conclusions:

  • Thoracic indices in pectus excavatum are significantly influenced by the respiratory phase.
  • The end-expiratory phase of quiet expiration is recommended for consistent and reliable thoracic index assessment.
  • Real-time MRI is effective in characterizing chest wall dynamics in pectus excavatum.