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The Pauli Exclusion Principle03:06

The Pauli Exclusion Principle

The arrangement of electrons in the orbitals of an atom is called its electron configuration. We describe an electron configuration with a symbol that contains three pieces of information:
Machines01:19

Machines

Machines are complex structures consisting of movable, pin-connected multi-force members that work together to transmit forces. One example of a machine is the cutting plier, which is used to cut wires by applying forces to its handles. When equal and opposite forces are exerted on the handles of the cutting plier, they cause the cutting edges to come together and apply equal and opposite reaction forces on the wire, which are greater than the applied forces.
A free-body diagram of the...
Machines: Problem Solving I01:22

Machines: Problem Solving I

A toggle clamp is a mechanical device commonly used for holding and clamping objects in various applications, such as woodworking, metalworking, and assembly operations. Consider a toggle clamp subjected to a force of 200 N at the handle. The vertical clamping force can be calculated, provided the dimensions of the toggle clamp are known.
The toggle clamp system is a machine structure consisting of movable, pin-connected multi-force members that form a stabilized system to transmit forces. The...
Machines: Problem Solving II01:30

Machines: Problem Solving II

Machines are complex structures consisting of movable, pin-connected multi-force members that work together to transmit forces. Consider a lifting tong carrying a 100 kg load. It comprises movable sections DAF and CBG linked together with member AB.
Chambers of the Heart01:16

Chambers of the Heart

The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
Freudian Psychology01:26

Freudian Psychology

Sigmund Freud, an Austrian neurologist born in 1856, significantly influenced psychology through his exploration of the unconscious mind. His interest in patients suffering from hysteria and neurosis — conditions without apparent physical causes — led him to theorize the existence of an unconscious mind, a repository for feelings and urges beyond our awareness. Freud's innovative approach included techniques such as dream analysis, free association, and attention to slips of the tongue to...

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Articles linked to this work by shared authors, journal, and citation graph.

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Structure of human phospholipase D3, a single-strand exonuclease associated with Alzheimer's disease.

The FEBS journal·2024
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Fus-SMO: Kinetics, Biochemical Characterisation and In Silico Modelling of a Chimeric Styrene Monooxygenase Demonstrating Quantitative Coupling Efficiency.

Chembiochem : a European journal of chemical biology·2024
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Loop 6 and the β-hairpin flap are structural hotspots that determine cofactor specificity in the FMN-dependent family of ene-reductases.

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In conversation with Lori Passmore.

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Regioselective Biocatalytic C4-Prenylation of Unprotected Tryptophan Derivatives.

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The emerging role of dipeptidyl peptidase 3 in pathophysiology.

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Related Experiment Video

Updated: Jul 2, 2026

Christopher Hughes: An in vitro model for the Study of Angiogenesis (Interview)
10:29

Christopher Hughes: An in vitro model for the Study of Angiogenesis (Interview)

Published on: April 28, 2007

In conversation with Peter Macheroux.

Eleni Skourti1, Peter Macheroux2

  • 1The FEBS Journal Editorial Office, Cambridge, UK.

The FEBS Journal
|October 29, 2022
PubMed
Summary

Professor Peter Macheroux

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Biotechnology

Background:

  • Research spans bacterial enzymology, plant physiology, and human pathophysiology.
  • Focus on molecular pathways and enzymatic mechanisms.

Observation:

  • Identified dipeptidyl peptidase 3 (DPP3) as a biomarker for cardiovascular diseases.
  • Investigated the role of enzymes in various biological processes.

Findings:

  • DPP3 recognition as a cardiovascular disease biomarker.
  • Exploration of therapeutic strategies targeting DPP3.

Implications:

  • Potential for novel cardiovascular disease diagnostics and therapeutics.
  • Advancing understanding of enzyme function in human health and disease.

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