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Comprehensive and reliable sonographic assessment and scoring system for inflammatory lesions of the paediatric ankle
Patricia Vega-Fernandez1, Deirdre De Ranieri2, Edward Oberle3
1Division of Rheumatology, Department of Pediatrics, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Insights
A new ultrasound (US) protocol and scoring system were developed for assessing paediatric ankle synovitis and tenosynovitis. This reliable bedside tool aids clinical decision-making in juvenile idiopathic arthritis.
Area of Science:
- Pediatric Rheumatology
- Musculoskeletal Ultrasound
- Medical Imaging
Background:
- Clinical decision-making in pediatric arthritis lacks objective bedside imaging tools.
- Standardized ultrasound (US) protocols are needed for evaluating pediatric ankle inflammation.
Approach:
- Developed a standardized US scanning protocol for pediatric ankle synovitis and tenosynovitis.
- 19 pediatric rheumatologists established standardized views and scoring systems.
- Assessed inter-rater reliability using intraclass correlation coefficients (ICC) on still images and a practical exercise.
Key Points:
- A nine-view protocol for B-mode and Doppler assessment was finalized.
- Highly reliable scoring systems were achieved for the anterior tibiotalar joint (ICC: 0.93), talonavicular joint (ICC: 0.86), subtalar joint (ICC: 0.91), and tendons (ICC: 0.96).
Conclusions:
- A comprehensive and reliable pediatric ankle US protocol and scoring system for synovitis and tenosynovitis were successfully developed.
- This validated scoring system can serve as an outcome measure in clinical and research settings.
Objective:
The clinical decision-making process in paediatric arthritis lacks an objective, reliable bedside imaging tool. The aim of this study was to develop a US scanning protocol and assess the reliability of B-mode and Doppler scoring systems for inflammatory lesions of the paediatric ankle.
Methods:
As part of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) US group, 19 paediatric rheumatologists through a comprehensive literature review developed a set of standardized views and scoring systems to assess inflammatory lesions of the synovial recesses as well as tendons of the paediatric ankle. Three rounds of scoring of still images were followed by one practical exercise. Agreement among raters was assessed using two-way single score intraclass correlation coefficients (ICC).
Results:
Of the 37 initially identified views to assess the presence of ankle synovitis and tenosynovitis, nine views were chosen for each B-mode and Doppler mode semi-quantitative evaluation. Several scoring exercises and iterative modifications resulted in a final highly reliable scoring system: anterior tibiotalar joint ICC: 0.93 (95% CI 0.92, 0.94), talonavicular joint ICC: 0.86 (95% CI 0.81, 0.90), subtalar joint ICC: 0.91 (95% CI 0.88, 0.93) and tendons ICC: 0.96 (95% CI 0.95, 0.97).
Conclusion:
A comprehensive and reliable paediatric ankle US scanning protocol and scoring system for the assessment of synovitis and tenosynovitis were successfully developed. Further validation of this scoring system may allow its use as an outcome measure for both clinical and research applications.
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