Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

5.3K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.3K
Embryonic Stem Cells00:57

Embryonic Stem Cells

3.7K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
3.7K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.2K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.2K
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

4.3K
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
4.3K
iPS Cell Differentiation01:22

iPS Cell Differentiation

2.8K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.8K
Forced Transdifferentiation01:28

Forced Transdifferentiation

1.9K
Transdifferentiation, also known as lineage reprogramming, was first discovered by Selman and Kafatos in 1974 in silkmoths. They observed that the moths’ cuticle-producing cells transformed into salt-producing cells. Many such cases of natural transdifferentiation occur in organisms. In humans, pancreatic alpha cells can become beta cells. In newts, the loss of the eye’s lens causes the pigmented epithelial cells to transdifferentiate into the lens cells.
Artificial...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sequential intracellular delivery of genetic coding molecules using an acoustic electric microfluidic platform.

Lab on a chip·2026
Same author

Glioma chemotherapeutic resistance is tied to membrane electrophysiological properties and glycosylation.

Bioengineering & translational medicine·2026
Same author

Non-Uniform Electric Field Manipulation of Chromogenic Peptide Amphiphile Assemblies.

ChemSystemsChem·2025
Same author

Label-Free Sorting of Human Mesenchymal Stem Cells Using Insulating Dielectrophoresis.

Electrophoresis·2025
Same author

Electrical Phenotyping of Aged Human Mesenchymal Stem Cells Using Dielectrophoresis.

Micromachines·2025
Same author

Dielectrophoretic Microfluidic Designs for Precision Cell Enrichments and Highly Viable Label-Free Bacteria Recovery from Blood.

Micromachines·2025

Related Experiment Video

Updated: Aug 23, 2025

Author Spotlight: Advancements in Synthetic Genetic Devices for Stem Cell Fate Manipulation and Cellular Therapy Development
06:04

Author Spotlight: Advancements in Synthetic Genetic Devices for Stem Cell Fate Manipulation and Cellular Therapy Development

Published on: December 8, 2023

1.2K

It's Electric: When Technology Gives a Boost to Stem Cell Science.

Abraham P Lee1, Mohammad Aghaamoo2, Tayloria N G Adams3

  • 1Departments of Biomedical Engineering and Mechanical & Aerospace Engineering, NSF I/UCRC, Center for Advanced Design & Manufacturing of Integrated Microfluidics (CADMIM), Biomolecular Microsystems and Nano Transducers (BioMiNT) Lab, 3120 Natural Sciences II, Irvine, CA 92697-2715, USA.

Current Stem Cell Reports
|October 31, 2022
PubMed
Summary

Electrokinetic techniques enable label-free analysis and separation of stem cells by probing inherent properties. This advances stem cell research and regenerative medicine applications without cell damage.

Keywords:
AnalysisDielectrophoresisImpedanceMembrane capacitanceSeparationStem cell

More Related Videos

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System
08:00

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

Published on: May 14, 2015

31.8K
Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

7.8K

Related Experiment Videos

Last Updated: Aug 23, 2025

Author Spotlight: Advancements in Synthetic Genetic Devices for Stem Cell Fate Manipulation and Cellular Therapy Development
06:04

Author Spotlight: Advancements in Synthetic Genetic Devices for Stem Cell Fate Manipulation and Cellular Therapy Development

Published on: December 8, 2023

1.2K
Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System
08:00

Scalable 96-well Plate Based iPSC Culture and Production Using a Robotic Liquid Handling System

Published on: May 14, 2015

31.8K
Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy
10:16

Assessing Stem Cell DNA Integrity for Cardiac Cell Therapy

Published on: January 25, 2019

7.8K

Area of Science:

  • Stem cell biology
  • Biophysics
  • Regenerative Medicine

Background:

  • Advanced technologies offer novel approaches to stem cell research.
  • Electrokinetic techniques utilize electric fields to study or separate cells.
  • These methods probe intrinsic cell properties, eliminating the need for specific labels.

Purpose of the Study:

  • To review the application of electrokinetic techniques in stem cell science.
  • To highlight insights gained into stem cell function using these methods.
  • To explore the potential of label-free techniques in stem cell research.

Main Methods:

  • Application of electrokinetic techniques to various stem cell types.
  • Analysis of inherent cell properties for cell identification and sorting.
  • Label-free enrichment and separation of stem cells.

Main Results:

  • Electrokinetic analysis revealed distinct, fate-specific signatures in stem cells.
  • Label-free enrichment of stem cells was achieved based on inherent properties.
  • These techniques demonstrated no cell damage or toxicity.

Conclusions:

  • Label-free electrokinetic techniques provide powerful tools for stem cell analysis and sorting.
  • These methods open new avenues for understanding stem cell biology.
  • Optimizing stem cell use in regenerative medicine is facilitated by these advancements.