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Author Spotlight: Advancing Antiviral Strategies Through Novel Immunocapture and Mass Spectrometry Techniques
Published on: January 12, 2024
Detection of SARS-COV-2 by functionally imprinted micelles
Lance R Hubbard1, Caleb J Allen1, Amy C Sims1
1Pacific Northwest National Laboratory, Richland, Washington, DC USA.
Abstract:
The near real-time detection of airborne particles-of-interest is needed for avoiding current/future threats. The incorporation of imprinted particles into a micelle-based electrochemical cell produced a signal when brought into contact with particle analytes (such as SARS-COV-2), previously imprinted onto the structure. Nanoamp scales of signals were generated from what may've been individual virus-micelle interactions. The system showed selectivity when tested against similar size and morphology particles. The technology was compatible with airborne aerosol sampling techniques. Overall, the application of imprinted micelle technology could provide near real-time detection methods to a host of possible analytes of interest in the field.
Supplementary Information:
The online version contains supplementary material available at 10.1557/s43579-022-00242-0.
