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Updated: Aug 23, 2025

A Rat Carotid Artery Pressure-Controlled Segmental Balloon Injury with Periadventitial Therapeutic Application
Published on: July 9, 2020
Case report: Unusual persistent hypotension and acute occlusion after peripheral paclitaxel balloon angioplasty
Lin Yang1, Jianlin Liu1, Chao Liu1
1Department of Vascular Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Background:
Paclitaxel-coated balloon (PCB) angioplasty is a mainstream treatment for peripheral artery disease; however, the safety of PCB remains controversial.
Case Presentation:
We confirmed acute occlusion during PCB angioplasty in a patient with femoropopliteal artery occlusion. The occluded vessels were revascularized completely after endovascular medical therapy and bailout stenting angioplasty. Then, the patient experienced persistent post-procedure orthostatic hypotension (30 days) and received hydration and vasoactive agents with a target mean arterial blood pressure of 75-85 mmHg. The patient's blood pressure gradually recovered over the 30 days after the procedure, and there was no recurrence of symptomatic hypotension during the follow-up.
Conclusions:
This rare complication is helpful to evaluate the safety of the PCB device.
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