Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

7.8K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
7.8K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.4K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative Assessment of Respiratory-Induced Clinical Target Volume Motion During Postoperative Whole-Breast Radiotherapy Using Four-Dimensional Computed Tomography.

Cancers·2026
Same author

Differential Association of Visceral and Subcutaneous Adipose Tissue with Treatment Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.

Diagnostics (Basel, Switzerland)·2026
Same author

Prospective Multimodal Assessment of Radiation-Induced Subclinical Cardiac Changes in Patients with Left Breast Cancer Using Hematologic Biomarkers, Echocardiography, and <sup>18</sup>F-FDG PET/CT: A Pilot Study.

Cancers·2026
Same author

Changes of F-18 fluorodeoxyglucose positron emission tomography/computed tomography textural features in temporal lobe after radiotherapy for nasopharyngeal carcinoma.

International journal of radiation biology·2026
Same author

Prognostic Value of FDG PET/CT Parameters in Patients With Advanced Biliary Tract Cancer Receiving Gemcitabine, Cisplatin, and Nab-Paclitaxel.

Clinical nuclear medicine·2026
Same author

Association Between Lung Volume Reduction and Symptomatic Radiation Pneumonitis in Lung Cancer Patients Undergoing Definitive Concurrent Chemoradiotherapy.

Clinical lung cancer·2025

Related Experiment Video

Updated: Aug 23, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.5K

Prostate only radiotherapy using external beam radiotherapy: A clinician's perspective.

Jeong Won Lee1, Mi Joo Chung2

  • 1Department of Radiation Oncology, Daegu Catholic University School of Medicine, Daegu 42472, South Korea.

World Journal of Clinical Cases
|October 31, 2022
PubMed
Summary

Prostate-only radiotherapy (PORT) offers effective tumor control for localized prostate cancer. Advances in external beam radiation therapy (RT) techniques improve outcomes while minimizing side effects, though optimal treatment management requires further clinical consideration.

Keywords:
Prostate cancerRadiation doseRadiation techniqueRadiation volumeRadiotherapy

More Related Videos

Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.2K
Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant
05:18

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

1.5K

Related Experiment Videos

Last Updated: Aug 23, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
08:34

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

20.5K
Stereotactic Radiosurgery for Gynecologic Cancer
10:35

Stereotactic Radiosurgery for Gynecologic Cancer

Published on: April 17, 2012

18.2K
Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant
05:18

Author Spotlight: Improving Radiation Therapy Access with Radiation Planning Assistant

Published on: October 6, 2023

1.5K

Area of Science:

  • Oncology
  • Radiation Oncology
  • Medical Physics

Background:

  • Prostate-only radiotherapy (PORT) is a standard definitive treatment for localized prostate cancer.
  • Prostate cancer's radiobiology favors larger fraction sizes for effective tumor control.
  • External beam radiation therapy (RT) techniques have evolved significantly, improving precision and reducing toxicity.

Purpose of the Study:

  • To review the radiobiological principles underpinning PORT.
  • To discuss advancements in external beam RT techniques for localized prostate cancer.
  • To provide a clinician's perspective on managing RT volume and dose, considering patient factors.

Main Methods:

  • Review of current literature on prostate-only radiotherapy.
  • Analysis of radiobiological data relevant to prostate cancer.
  • Evaluation of technological advancements in external beam radiation therapy (e.g., IMRT, SBRT, IG-RT).

Main Results:

  • External beam RT techniques have evolved, leading to improved local control and reduced toxicity.
  • Intensity-modulated RT (IMRT) and stereotactic body RT (SBRT) have demonstrated efficacy and safety.
  • Dose escalation strategies, enabled by advanced RT techniques, show promise for enhanced tumor control.

Conclusions:

  • Modern external beam RT techniques enhance the efficacy and safety of PORT for localized prostate cancer.
  • Further elucidation of RT management, including volume and dose considerations based on patient characteristics, is necessary.
  • A clinician's perspective is crucial for optimizing PORT strategies in localized prostate cancer.