Related Experiment Video
Updated: Aug 23, 2025

09:43
Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids
Published on: October 14, 2019
6.6K
Wandering small intestinal stromal tumor: A case report
Jin-Zhan Su1, Shu-Feng Fan1, Xia Song2
1Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310005, Zhejiang Province, China.
World Journal of Clinical Cases
|October 31, 2022
Summary
A rare wandering small intestinal stromal tumor (GIST) was diagnosed in a patient presenting with bleeding. This case highlights the importance of considering GIST migration when tumors are not found in their typical location.
Area of Science:
- Gastroenterology
- Surgical Oncology
- Radiology
Background:
- Gastrointestinal stromal tumors (GISTs) are rare in the small intestine.
- Wandering GISTs, tumors not found in their original location, are exceptionally uncommon.
- Disseminating this case aids future diagnosis and treatment strategies for GISTs.
Observation:
- A 68-year-old patient presented with symptoms of gastrointestinal bleeding (tarry stools).
- Imaging revealed a mobile tumor within the abdominal cavity, suggesting a wandering mass.
- Initial management focused on hemostasis via angiography and embolization due to patient instability.
Findings:
- Histological examination confirmed a submucosal GIST with infarction, classified as intermediate-risk.
- Immunohistochemistry showed positive markers for CD117, Dog1, CD34, and SMA.
- The final diagnosis was a wandering small intestinal GIST.
Implications:
- Clinicians should consider GISTs in highly vascularized small intestinal tumors.
- The possibility of tumor migration must be evaluated if the primary tumor site is unclear.
- This case contributes to understanding the rare phenomenon of wandering GISTs.

