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Subaortic Membrane Co-existing With Hypertrophic Cardiomyopathy: A Clinically Challenging Diagnosis

Mehr Un Nisa Farhan1, Hamza Akhtar2, Hussein Al Sudani3

  • 1Internal Medicine, Shaikh Khalifa Bin Zayed Al-Nahyan Medical and Dental College, Lahore, PAK.

Cureus
|October 31, 2022
PubMed

Insights

This report details a rare case of subaortic membrane coexisting with hypertrophic obstructive cardiomyopathy (HOCM). This combination caused significant left ventricular outflow tract obstruction in an 18-year-old male.

Area of Science:

  • Cardiology
  • Medical Diagnostics
  • Rare Disease Research

Background:

  • Subaortic membrane is a common cause of subaortic stenosis.
  • Hypertrophic obstructive cardiomyopathy (HOCM) is a distinct cardiac condition.
  • The co-occurrence of these two conditions is exceptionally rare and often underdiagnosed.

Observation:

  • An 18-year-old male presented with chest pain and dyspnea.
  • The patient exhibited symptoms attributed to both fixed and dynamic left ventricular outflow tract (LVOT) obstruction.
  • Diagnostic evaluation revealed the presence of a subaortic membrane and HOCM.

Findings:

  • The patient had a fixed obstruction due to a subaortic membrane.
  • The patient also had dynamic obstruction caused by HOCM.
  • Combined LVOT obstruction from both pathologies led to significant clinical symptoms.

Implications:

  • This case highlights the importance of considering rare combined pathologies in diagnosing LVOT obstruction.
  • Accurate diagnosis is crucial for appropriate management of patients with complex cardiac conditions.
  • Further research may elucidate the pathophysiology and optimal treatment strategies for this rare combination.

Keywords:
echocardiographyhypertrophic cardiomyopathylvot obstructionsamsubaortic membrane

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