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Assessment of Blood Pressure Variability in Postmenopausal Women

Ayushi Jain1, Sunil Kumar1, Sourya Acharya1

  • 1Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, IND.

Cureus
|October 31, 2022
PubMed

Insights

Blood pressure variability in postmenopausal women is linked to increased body mass index (BMI) and neck circumference. These factors, along with lipid changes, are independent contributors to cardiovascular risk in this demographic.

Area of Science:

  • Cardiovascular Health
  • Menopause Research
  • Metabolic Syndrome

Background:

  • Elevated blood pressure is a primary cause of cardiovascular and cerebrovascular disease.
  • Blood pressure variability is an independent risk factor for cardiovascular events in menopausal women.
  • Estrogen decline during menopause disrupts metabolic pathways, increasing insulin resistance, BMI, and dyslipidemia.

Purpose of the Study:

  • To assess blood pressure variability in postmenopausal women.
  • To investigate the association between blood pressure variability and Body Mass Index (BMI).

Main Methods:

  • A cross-sectional study included 175 postmenopausal females over 50 years old.
  • Blood pressure (diastolic and systolic) was recorded manually at 6 am, 12 pm, and 7 pm.
  • Body Mass Index (BMI), neck circumference, and lipid profiles were also measured.

Main Results:

  • Systolic and diastolic blood pressure variations were recorded at different times of the day.
  • Blood pressure showed specific readings in association with BMI over 25 kg/m².
  • Similar blood pressure patterns were observed with neck circumference greater than 32 cm.

Conclusions:

  • Increased BMI and neck circumference are independently associated with blood pressure variability in menopausal women.
  • Elevated triglyceride and cholesterol levels may also independently contribute to blood pressure variability.
  • These findings highlight key factors influencing cardiovascular risk in postmenopausal women.
Abstract

Keywords:
agingblood pressurecardiovascularmenopausevariation

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