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Related Experiment Video

Updated: Aug 23, 2025

Preterm EEG: A Multimodal Neurophysiological Protocol
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Neonatal Frequency-Following Responses: A Methodological Framework for Clinical Applications.

Natàlia Gorina-Careta1,2,3,4, Teresa Ribas-Prats1,2,3, Sonia Arenillas-Alcón1,2,3

  • 1Brainlab - Cognitive Neuroscience Research Group, Department of Clinical Psychology and Psychobiology, University of Barcelona, Catalonia, Spain.

Seminars in Hearing
|October 31, 2022
PubMed
Summary

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Rhythmicity and Trait Absorption Are Linked to Nonordinary States of Consciousness.

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Neural adaptation in brain responses to vocal and emotional sounds in school-age children.

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Bilingual Exposure and Sex Shape Developmental Trajectories of Brain Responses to Speech-Sound Features in Infants.

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Toward the Optimal Stimulus to Elicit the Frequency-Following Response.

Ear and hearing·2025

The neonatal frequency-following response (FFR) can be recorded in newborns to predict language development. This auditory evoked potential aids in early identification and intervention for potential sound and language encoding disorders.

Area of Science:

  • Auditory Neuroscience
  • Developmental Audiology

Background:

  • The frequency-following response (FFR) is a noninvasive auditory evoked potential reflecting neural activity synchronized to sound.
  • FFR shows promise for understanding sound encoding, language development, and communication.
  • Neonatal FFR is particularly valuable for early identification of language disorders and leveraging brain plasticity.

Purpose of the Study:

  • To review the current state of neonatal FFR research.
  • To present practical methods for recording FFR in clinical settings.
  • To highlight the applications and predictive potential of neonatal FFR.

Main Methods:

  • Review of existing literature on neonatal FFR.
  • Description of methodological approaches for clinical FFR recording.
Keywords:
brainstem responseinfantsnewbornsspeech ABRspeech encoding

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  • Synthesis of findings based on extensive research experience.

    • Main Results:

    • Neonatal FFR is feasible to record shortly after birth.
    • FFR can predict short- and long-term language abilities.
    • Early identification of language disruptions is possible through neonatal FFR.

    Conclusions:

    • The review comprehensively covers neonatal FFR applications.
    • Recording FFR in the first days of life is feasible.
    • Neonatal FFR holds significant predictive value for language development and disorders.