Related Experiment Video
Updated: Aug 23, 2025

An Educational Video Demonstration of How to Prone a Critically Ill Intubated Patient
Published on: November 30, 2022
'Propped and prone' positioning reduces respiratory events in spontaneously breathing preterm infants: A randomised
Christopher M Richmond1,2,3, Fabian Ring1, Lacey Richmond1,4
1Newborn Care Unit, Gold Coast University Hospital, Gold Coast, Queensland, Australia.
Insights
Propped/prone infant positioning significantly reduced respiratory events and improved oxygen saturation in preterm infants. Continuous pump feeds did not show significant benefits over standard bolus feeding methods.
Area of Science:
- Neonatal Medicine
- Pediatric Respiratory Care
- Infant Physiology
Background:
- Preterm infants (<32 weeks gestation) are susceptible to respiratory events and hypoxemia.
- Current management in neonatal units includes positioning and feeding strategies.
- Optimizing these interventions is crucial for improving outcomes.
Purpose of the Study:
- To compare the effects of infant positioning and feed-rate interventions on respiratory events and oximetry in preterm infants.
- To evaluate the impact of propped/prone positioning versus supine positioning.
- To assess the efficacy of continuous pump feeds versus gravity bolus feeds.
Main Methods:
- Randomized triple crossover design with 68 preterm infants.
- Three conditions: control (supine/flat, gravity bolus feeds), position intervention (propped/prone), and feed-rate intervention (continuous pump feeds).
- Primary outcomes: number of respiratory events (apnea, bradycardia, desaturation) and time with SpO2 <80% over 24 hours. Secondary outcome: time with SpO2 ≥88%.
Main Results:
- Propped/prone positioning significantly reduced respiratory events compared to control and continuous pump feeds (P < 0.001).
- Improved percentage of time with SpO2 <80% and ≥88% in the propped/prone position (P < 0.001).
- No significant difference in outcomes between continuous pump feeds and gravity bolus feeds.
Conclusions:
- Alternative infant positioning, specifically propped/prone, is recommended for preterm infants in neonatal units.
- Positioning interventions offer a significant benefit for respiratory and oxygenation parameters.
- Feed-rate interventions did not demonstrate a significant advantage over standard methods in this study.
Aim:
We compared effects of infant positioning and feed-rate interventions on respiratory events and oximetry parameters in spontaneously breathing preterm infants born <32 weeks gestation managed in a neonatal unit.
Methods:
A randomised triple crossover design was employed. n = 68 infants underwent three test conditions A: control (supine/flat, gravity bolus feeds), B: position intervention (propped/prone) and C: feed-rate intervention (continuous pump feeds) in randomised sequence over three consecutive days. Primary outcomes were number of events (apnoea, bradycardia and desaturation) and percentage time SpO2 < 80% over 24 h. The secondary outcome was percentage time SpO2 ≥ 88%. Treatment effects were estimated using linear mixed-effects models.
Results:
Propped/prone positioning significantly reduced events and improved percentage time SpO2 < 80% and ≥88% compared to both other conditions (all P < 0.001). Outcomes for the feed-rate intervention were not significantly different to control.
Conclusions:
Alternative infant positioning should be considered in preterm infants managed in the neonatal unit.
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