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Uncharted surgical therapy for acquired perforating dermatoses
Mohammad Bashar Izzat1, Ali Kahila2, Ahmad Walid Izzat1
1Department of Surgery, 251087Faculty of Medicine, Damascus University, Damascus, Syria.
Abstract:
Acquired perforating dermatoses represent an uncommon group of chronic papulonodular dermatoses of unknown aetiology, characterized clinically by intense itching; and histopathologically by transepidermal elimination of dermal components. Definitive targeted pharmacological approaches are lacking, and the disease is usually refractory to therapy. We report here a case of rapid remission of acquired perforating dermatosis following simple thymectomy. If a role for the thymus in the pathogenesis of acquired perforating dermatoses was to be established, this could pave the way for a yet uncharted surgical therapy for these debilitating conditions.
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