Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

525
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
525
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

622
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
622
Glaucoma: Overview01:25

Glaucoma: Overview

696
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
696
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

6.3K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
6.3K
Myasthenia Gravis: Overview and Treatment01:20

Myasthenia Gravis: Overview and Treatment

1.8K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reversible Orbital Apex Syndrome.

Journal of eye movement research·2026
Same author

Variants in the WDR45 Gene Within the OPA-2 Locus Associate With Isolated X-Linked Optic Atrophy.

Investigative ophthalmology & visual science·2023
Same author

A Consensus Statement on the Terminology for Automated Visual Field Abnormalities.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2022
Same author

[TREATMENT DILEMMAS IN FULMINANT INTRACRANIAL HYPERTENSION].

Harefuah·2019
Same author

Familial juvenile normal-tension glaucoma with anterior segment dysgenesis: a clinical report of a new phenotype.

Journal of glaucoma·2012
Same author

Ocular motor and sensory function in Parkinson's disease.

Ophthalmology·2011
Same journal

[Tennis Elbow Among Players].

Harefuah·2026
Same journal

[Internal Medicine - My Mission].

Harefuah·2026
Same journal

[Treatment of Morbid Obesity in Israel: GLP-1 Agonists Versus Bariatric Surgery - Clinical and Economic Aspects].

Harefuah·2026
Same journal

[Baby steps: Post-operative Treatment Recommendations for Pediatric Tracheostomy in Israel].

Harefuah·2026
Same journal

[Mastoiditis Caused by Fusobacterium Necrophorum: an Unusual Pathogen in a Well-Known Disease].

Harefuah·2026
Same journal

[Cochlear Implantation in Single-Sided Deafness - Six Years of Follow-Up from Diagnosis and Consistent Use, Through Dedicated and Creative Auditory Learning, to the Development of Bilateral Central Processing Abilities].

Harefuah·2026
See all related articles

Related Experiment Video

Updated: Aug 23, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.2K

[OPTIC NEURITIS - CLASSIFICATION, MANAGEMENT AND TREATMENT].

Zina Almer1

  • 1Shamir (Assaf Harofeh) Medical Center.

Harefuah
|October 31, 2022
PubMed
Summary
This summary is machine-generated.

Optic neuritis, an optic nerve inflammation, can signal central nervous system diseases. Identifying the cause, like anti-aquaporin4 (AQP4) or anti-myelin oligodendrocyte glycoprotein (MOG) antibodies, is vital for treatment and preventing vision loss.

More Related Videos

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

654
Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
09:29

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

11.6K

Related Experiment Videos

Last Updated: Aug 23, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients
12:23

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

14.2K
Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
08:36

Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

Published on: April 19, 2024

654
Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
09:29

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4

Published on: August 21, 2017

11.6K

Area of Science:

  • Neurology
  • Immunology
  • Ophthalmology

Context:

  • Optic neuritis is an inflammatory optic nerve condition, often an early sign of central nervous system disorders.
  • Typical optic neuritis links to multiple sclerosis, but atypical forms have diverse causes.
  • Advances in identifying anti-aquaporin4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have refined understanding of neuromyelitis optica spectrum disorder (NMOSD) and MOG-associated disorder (MOGAD).

Purpose:

  • To highlight the evolving understanding and classification of atypical optic neuritis.
  • To emphasize the importance of accurate diagnosis for effective management and prognosis.
  • To underscore the role of specific antibody biomarkers in differentiating optic neuritis etiologies.

Summary:

  • Optic neuritis etiology varies, with idiopathic cases comprising one-third of diagnoses.
  • Distinguishing between typical and atypical optic neuritis is crucial as management and prognosis differ.
  • Identifying specific autoimmune markers like anti-AQP4 and anti-MOG antibodies is key for diagnosing NMOSD and MOGAD.

Impact:

  • Accurate and timely diagnosis of optic neuritis etiology is critical for initiating appropriate treatment.
  • Proper diagnosis aids in reducing long-term visual impairment and systemic disability.
  • Understanding the diverse causes of optic neuritis improves patient outcomes and management strategies.