Associations Among Sex, Cognitive Ability, and Autism Symptoms in Individuals with Down Syndrome
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Published on: April 22, 2015
Laura Del Hoyo Soriano1,2, Audra Sterling3, Jamie Edgin4
1MIND Institute, University of California Davis, 2825 50th Street, Sacramento, CA, USA. ldelhoyo@ucdavis.edu.
Abstract:
This study explores sex-differences in (a) rates and profiles of autism symptoms as well as in (b) the contribution of intellectual quotient (IQ) to autism symptom presentation in Down syndrome (DS). Participants were 40 males and 38 females with DS, aged 6 to 23 years. Autism symptoms were rated through the Autism Diagnostic Observation Schedule-Second Edition (ADOS-2). Results show no sex differences in the ADOS-2 Calibrated Severity Scores (CSS). However, only females with DS who are classified as DS-Only have higher scores on verbal IQ than those classified as DS + autism. Furthermore, associations between IQ and all CSSs are found for females, but not for males. Findings suggest that verbal cognition may play differential roles for females and males with DS.
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