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Radiotherapy for meningiomas.

William C Chen1,2, Haley K Perlow3, Abrar Choudhury4,5

  • 1Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, 94143, USA. william.chen@ucsf.edu.

Journal of Neuro-Oncology
|October 31, 2022
PubMed
Summary
This summary is machine-generated.

Meningioma radiotherapy is a key treatment alongside surgery. This review summarizes its history, current evidence, and future applications for these common brain tumors.

Keywords:
AnaplasticAtypicalDOTATATEMeningiomaMolecularRadiationRadiotherapy

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Area of Science:

  • Neuro-oncology
  • Radiation Oncology
  • Neurosurgery

Background:

  • Meningiomas are the most common primary central nervous system neoplasms.
  • Despite advances in understanding their diverse biology, treatment relies on surgery and radiation.
  • Current therapeutic strategies require further investigation into optimal radiotherapy application.

Purpose of the Study:

  • To review the historical context of meningioma radiotherapy.
  • To summarize the current evidence supporting radiotherapy in meningioma treatment.
  • To explore future directions for radiotherapy in managing meningiomas.

Main Methods:

  • Literature review of historical and current studies on meningioma radiotherapy.
  • Analysis of clinical evidence for radiotherapy efficacy and safety.
  • Discussion of emerging trends and future research in the field.

Main Results:

  • Radiotherapy has evolved significantly in treating meningiomas.
  • Current evidence supports its role in specific meningioma subtypes and settings.
  • Future applications may involve advanced techniques and personalized approaches.

Conclusions:

  • Maximal safe resection and radiotherapy remain the cornerstones of meningioma management.
  • Further research is needed to optimize radiotherapy protocols.
  • Radiotherapy holds significant potential for improving outcomes in meningioma patients.