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Dedifferentiated liposarcoma in the abdominal cavity: a case report
Marina Kuroda1, Reiko Yamada2, Takamitsu Tanaka3
1Department of Family Medicine, Mie Prefectural Ichishi Hospital, Tsu, Japan.
Clinical Journal of Gastroenterology
|October 31, 2022
Summary
Dedifferentiated liposarcoma of the mesentery is rare and challenging to diagnose. Surgical resection aids diagnosis, and genetic testing is crucial for developing new treatments for this rare cancer.
Area of Science:
- Oncology
- Surgical Pathology
Background:
- Liposarcoma, particularly dedifferentiated subtypes, can rarely originate in the mesentery.
- Mesenteric tumors pose diagnostic challenges due to their location and rarity.
Observation:
- A 70-year-old woman presented with a right lower abdominal mass.
- Initial imaging was insufficient for definitive diagnosis of the mesenteric mass.
Findings:
- Surgical resection confirmed dedifferentiated liposarcoma of the transverse colon with mesenteric origin.
- Cancer-specific genetic testing was performed, highlighting the potential for targeted therapies.
Implications:
- Surgical intervention is vital for accurate diagnosis of rare mesenteric liposarcomas.
- Genetic profiling is essential for advancing therapeutic strategies in dedifferentiated liposarcoma.

