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An economic evaluation of intensive hypertension control in CKD patients: a cost-effectiveness study
Ye Seol Lee1,2, Hae-Young Lee3, Tae Hyun Kim4
1Department of Rehabilitation Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Insights
Intensive hypertension control for chronic kidney disease (CKD) patients in Korea is economically sound. This approach increases quality-adjusted life years (QALYs) and is cost-effective for managing hypertension in CKD.
Area of Science:
- Health Economics
- Nephrology
- Cardiovascular Disease Management
Background:
- Intensive hypertension control shows potential effectiveness and economic feasibility in high cardiovascular disease (CVD) risk patients.
- Chronic kidney disease (CKD) patients with hypertension require specific management strategies.
Purpose of the Study:
- To conduct an economic evaluation of intensive hypertension control in Korean CKD patients.
- To compare the cost-effectiveness of intensive versus standard hypertension control in this population.
Main Methods:
- A Markov decision model was employed to compare costs and effectiveness.
- Model parameters were derived from Korean National Health Insurance Service (NHIS) data and existing literature.
- Sensitivity analysis was performed to assess the robustness of the findings.
Main Results:
- Intensive hypertension control in CKD patients incurs higher costs but yields increased quality-adjusted life years (QALYs).
- The incremental cost-effectiveness ratio (ICER) was projected at $18,126 per QALY.
- Sensitivity analysis confirmed the robustness of the economic evaluation.
Conclusions:
- Intensive hypertension control is an economically sound strategy for CKD patients in Korea.
- Findings provide valuable insights for clinicians and policymakers in hypertension management for CKD.
- This approach supports improved health outcomes and resource allocation.
Background:
Studies have suggested that intensive hypertension control in patients with a high risk of cardiovascular disease (CVD) is both effective and economically feasible. The purpose of this study is to conduct an economic evaluation of intensive hypertension control targeting chronic kidney disease (CKD) patients using the representative data in Korea.
Methods:
We used a Markov decision model to compare both cost and effectiveness of intensive hypertension control versus standard hypertension control in hypertensive CKD patients. Model parameters were estimated with the data from the National Health Insurance Service (NHIS)-National Sample Cohort, as well as latest literature. One-way sensitivity analysis was conducted to test the effect of variation in key parameters on the model outcome.
Results:
For CKD patients with hypertension, intensive hypertension control would cost more but increase utilities, compared to standard hypertension control. The incremental cost-effectiveness ratio (ICER) for intensive hypertension control in CKD patients was projected at 18,126 USDs per quality-adjusted life year (QALY) compared to standard hypertension control. The results of sensitivity analysis suggest that the results are overall robust.
Conclusions:
This study finds that intensive hypertension control in CKD patients in Korea is economically sound. This information is expected to be useful for clinicians in managing hypertension of CKD patients and policymakers when making decisions.
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