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A Case Report and Literature Review of Pseudo-TORCH Syndrome Type 2 (PTORCH2)
Rami A Misk1,2, Lama Qawasme3, Fawzy M Abunejma4
1College of Medicine and Health Sciences, Palestine Polytechnic University, Hebron, State of Palestine.
Abstract:
A pseudo-TORCH syndrome is a rare autosomal recessive disease characterized by intracranial calcification and microcephaly, leading to spasticity and seizures, but the serology of TORCH infection is negative. We present a 4-day-old female patient with jaundice, abnormal movement, and convulsions who was found to be homozygous for the missense USP18 gene mutation that causes pseudo-TORCH syndrome 2 (PTORCH2). The patient was managed with conservative measures.
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