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Microneedle patch tattoos.

Song Li1, Youngeun Kim1, Jeong Woo Lee1

  • 1School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.

Iscience
|November 1, 2022
PubMed
Summary
This summary is machine-generated.

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Microneedle (MN) patches offer a painless, bloodless method for applying medical tattoos, improving safety and accessibility. These innovative tattoos can store vital health information and enhance medical procedures.

Area of Science:

  • Biomaterials Science
  • Medical Devices
  • Dermatology

Background:

  • Medical tattoos convey crucial information, aid radiotherapy, and enhance cosmetic results but traditional needle injections cause pain, bleeding, and infection risks, limiting their use.
  • Current methods for medical tattooing are invasive and pose biohazardous waste concerns, hindering broader adoption and patient comfort.

Purpose of the Study:

  • To develop novel single-use microneedle (MN) patches for depositing medical tattoos in a safe, painless, and bloodless manner.
  • To create versatile MN patch tattoos capable of storing medical data, responding to physiological cues, and improving cosmetic outcomes.

Main Methods:

  • Development of single-use microneedle (MN) patches for transdermal tattoo delivery.
  • Design of MN patch tattoos incorporating numbers, letters, symbols, environmentally responsive inks, and QR codes.
Keywords:
BiomaterialsMedical biotechnologyMedical device

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  • Evaluation of tattoo retention, visibility (including UV-only), and data encoding capabilities.

    • Main Results:

    • MN patch tattoos were successfully applied painlessly and bloodlessly, eliminating biohazardous sharps waste.
    • Tattoos demonstrated retention for over one year and included features like UV-visible ink for privacy.
    • The MN patch tattoos effectively recorded medical conditions, vaccination status, and encoded complex personal health information.

    Conclusions:

    • Microneedle (MN) patch technology provides a safe, accessible, and user-friendly alternative for medical tattooing.
    • This innovation holds potential for improved fiducial marking, medical information storage, physiological monitoring, and cosmetic applications.