Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Drug Reactions01:27

Allergic Drug Reactions

931
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
931
Allergic Reactions02:06

Allergic Reactions

28.1K
Overview
28.1K
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

185
Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
185
Cross-reactivity00:42

Cross-reactivity

31.4K
Overview
31.4K
Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

481
While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
481
General Anesthesia: Overview01:24

General Anesthesia: Overview

270
Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
270

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of the Gendolcat model for chronic postsurgical pain after cesarean section: a multicenter study.

Minerva anestesiologica·2026
Same author

Successful reversal of hepatic visceral crisis in HER2-positive metastatic breast cancer: a case report.

Frontiers in oncology·2026
Same author

Chronic postsurgical pain after cesarean section and the importance of anticipation.

Regional anesthesia and pain medicine·2026
Same author

Cibisatamab and FAP-4-1BBL in microsatellite-stable colorectal cancer: a phase 1b trial.

Nature medicine·2026
Same author

Acute Postoperative Pain After Caesarean Section, Intensity and Management: A Cohort Multicentre Study.

European journal of pain (London, England)·2025
Same author

Ipatasertib combined with non-taxane chemotherapy for patients with previously treated advanced triple-negative breast cancer: the PATHFINDER phase IIa trial.

Breast cancer research : BCR·2025

Related Experiment Video

Updated: Aug 23, 2025

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

16.5K

Do cross-food allergies to propofol exist?

Carles Espinós Ramírez1,2, Marta Viñas Domingo1, Anna Peig Font1,2

  • 1Department of Anesthesiology, Consorci Sanitari de Terrassa, Terrassa, Spain.

Anesthesia and Pain Medicine
|November 1, 2022
PubMed
Summary

Propofol, an anesthetic, is generally safe for patients with soy, egg, or peanut allergies. Skin testing revealed a very low allergy rate, confirming its safe use in these populations.

Keywords:
EggFood allergyFood sensitizationPeanutsPropofolSoy

More Related Videos

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

25.7K
Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

17.7K

Related Experiment Videos

Last Updated: Aug 23, 2025

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

16.5K
Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

25.7K
Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

17.7K

Area of Science:

  • Anesthesiology
  • Clinical Immunology
  • Pharmacology

Background:

  • Propofol is a widely used intravenous anesthetic agent.
  • It is formulated as a lipid emulsion containing soybean oil, egg phosphatide, and egg lecithin.
  • Package labeling contraindicates propofol in patients with soy, egg, or peanut allergies due to potential cross-reactivity.

Purpose of the Study:

  • To investigate the safety of propofol administration in patients with confirmed food allergies.
  • To determine the prevalence of propofol allergy in individuals with documented allergies to soy, eggs, or peanuts.

Main Methods:

  • Inclusion of patients of all ages with confirmed allergies to soy, eggs, or peanuts.
  • Performance of skin testing to validate existing food allergies.
  • Subsequent skin testing with propofol for eligible candidates with positive food allergy tests.

Main Results:

  • Sixty-four patients with confirmed food allergies participated in propofol skin testing.
  • Only one patient (1.6%) showed a positive reaction to propofol skin testing.
  • The positive case involved a patient with documented allergies to both peanuts and soybeans.

Conclusions:

  • Propofol administration is considered safe for patients with allergies to soy, eggs, or peanuts.
  • Caution is advised for patients with a history of anaphylaxis following ingestion of these foods.
  • The study suggests no contraindication for propofol use based solely on common food allergies.