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Deep Eutectic Solvent-Enabled Plasmonic Nanocellulose Aerogel: On-Demand Three-Dimensional (3D) SERS Hotspot Based on
Sandeep Surendra Panikar1, Kolli Chandra Sekhar Reddy2,3, Ana L Gonzalez4
1Centro de Física Aplicada y Tecnología Avanzada (CFATA), Universidad Nacional Autónoma de México (UNAM), Querétaro, 76230, México.
Analytical Chemistry
|November 1, 2022
Summary
Researchers developed sustainable, 3D plasmonic aerogels using deep eutectic solvent and gold nanoparticles for on-demand surface-enhanced Raman scattering (SERS) detection. This innovative method offers enhanced sensitivity for analyzing liquid samples, including pesticides and dyes.
Area of Science:
- Materials Science
- Analytical Chemistry
- Nanotechnology
Background:
- Surface-enhanced Raman scattering (SERS) requires specific substrate designs for optimal hotspot generation.
- Conventional SERS substrates often lack the sensitivity and on-demand capabilities needed for complex sample analysis.
Purpose of the Study:
- To develop a sustainable and highly sensitive SERS substrate using a 3D plasmonic aerogel.
- To demonstrate an on-demand hotspot formation mechanism for enhanced analyte detection.
- To evaluate the performance of the fabricated aerogels for detecting pesticides and dyes in real-world samples.
Main Methods:
- Fabrication of 3D plasmonic aerogels using deep eutectic solvent (DES), gold nanoparticles (AuNPs), and cellulose nanocrystals (CNCs).
- Investigation of the on-demand SERS mechanism through theoretical calculations and experimental validation.
- Quantification of organophosphorus pesticides (edifenphos, parathion) in rice and tea extracts.
- Detection of Methylene Blue in fish muscle extract.
Main Results:
- The 3D plasmonic aerogels demonstrated exceptional SERS enhancement compared to 2D substrates.
- An on-demand hotspot formation mechanism was confirmed, triggered by analyte solution loading.
- Achieved a low detection limit of 9.8 nM for Methylene Blue in fish muscle extract.
- Successfully detected pesticides in complex food matrices.
Conclusions:
- The developed 3D plasmonic aerogels offer a sustainable and effective platform for on-demand SERS sensing.
- This approach significantly improves sensitivity and detection limits for analyzing liquid samples.
- The use of green solvents and biobased materials highlights a sustainable framework for future analytical applications.
