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Related Concept Videos

Chemical Signaling in the Endocrine System01:08

Chemical Signaling in the Endocrine System

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A signaling cascade is a series of events that facilitates the transmission of information within or between cells, culminating in a targeted response in the recipient cell. As chemical messengers, hormones are pivotal in initiating and modulating these intricate signaling cascades based on their solubility.
Lipid-soluble hormones, such as steroid hormones, demonstrate an intracellular action. These hormones traverse cell membranes due to their lipid nature. Once inside the target cell, they...
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Types of Toxins01:36

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Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
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What is the Endocrine System?00:46

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The endocrine system sends hormones—chemical signals—through the bloodstream to target cells—the cells the hormones selectively affect. These signals are produced in endocrine cells, secreted into the extracellular fluid, and then diffuse into the blood. Eventually, they diffuse out of the blood and bind to target cells which have specialized receptors to recognize the hormones.
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An Overview of the Endocrine System01:10

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The endocrine system, a complex network of glands, orchestrates physiological balance within the body through the production and secretion of hormones. These hormones are chemical messengers in intercellular communication, acting as conduits between the secretory cells and distant target sites. They traverse the circulatory system by being released into the extracellular fluid, and their impact is specific to cells possessing receptors for a particular hormone.
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Structures of the Endocrine System00:59

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The intricate framework of the endocrine system encompasses a diverse array of glands, with their target tissues and organs strategically distributed throughout the body. Central to this network are the endocrine glands, specialized structures that lack ducts and release hormones directly into the interstitial fluid. Notably, the hypothalamus, a vital neuroendocrine organ situated in the brain, governs neural functions and serves as a potent source of hormonal regulation. Near the hypothalamus...
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The endocrine system is an extensive network of glands – organs or tissues in the body that create chemicals that control many bodily functions, that secrete hormones, which are chemical messengers that play essential roles in regulating various bodily functions. These hormones are secreted into the bloodstream and travel throughout the body. They require specific receptors to convey signals to cells possessing these corresponding receptors. This complex signaling mechanism ensures that...
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Updated: Aug 23, 2025

Methods to Test Endocrine Disruption in Drosophila melanogaster
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[Endocrine Disrupting Chemicals].

Lydia Kürzinger1, Martin Fassnacht1, Ulrich Dischinger1

  • 1Medizinische Klinik und Poliklinik I, Lehrstuhl für Endokrinologie und Diabetologie, Universitätsklinikum Würzburg.

Deutsche Medizinische Wochenschrift (1946)
|November 1, 2022
PubMed
Summary

Endocrine disrupting chemicals (EDCs) are widespread substances that can interfere with hormones. Even at low doses, EDCs pose risks to human health and the environment, necessitating better regulation.

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Area of Science:

  • Environmental Science
  • Toxicology
  • Endocrinology

Background:

  • Endocrine disrupting chemicals (EDCs) are ubiquitous environmental contaminants.
  • EDCs can interfere with the endocrine system, mimicking or blocking natural hormones.
  • Their effects can occur at very low exposure levels, posing challenges for toxicological assessment.

Conclusions:

  • Standardized definitions and rigorous assessment of EDCs are crucial.
  • Effective regulation is needed to mitigate the widespread risks of EDCs.
  • Further research is essential to understand and address the full scope of EDC impacts.