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Updated: Aug 19, 2026

Development of a More Sensitive and Specific Chromogenic Agar Medium for the Detection of Vibrio parahaemolyticus and Other Vibrio Species
09:34

Development of a More Sensitive and Specific Chromogenic Agar Medium for the Detection of Vibrio parahaemolyticus and Other Vibrio Species

Published on: November 8, 2016

[Vibrio and aeromonad sensitivity to the vibriostatic O 129]

A B Khaĭtovich, E A Ved'mina

    Antibiotiki I Meditsinskaia Biotekhnologiia = Antibiotics and Medical Biotechnology
    |June 1, 1987
    PubMed

    Insights

    Vibriostatic O129 effectively inhibits Vibrio cholerae and Vibrio albensis. However, some halophilic vibrios, Aeromonas, and Plesiomonas species exhibit resistance, making O129 a useful taxonomic differentiator.

    Area of Science:

    • Microbiology
    • Bacteriology
    • Taxonomy

    Context:

    • The study investigated the antimicrobial susceptibility of bacterial isolates from the USSR.
    • Vibriostatic O129 (2,4-diamino-6,7-diisopropyl pteridine) was used to assess sensitivity.
    • Testing involved disks with 10 and 150 micrograms of the drug.

    Purpose:

    • To determine the sensitivity of Vibrio and Aeromonas species to vibriostatic O129.
    • To evaluate vibriostatic O129 as a potential taxonomic criterion for differentiating bacterial genera and species.
    • To assess the utility of vibriostatic O129 in distinguishing between Vibrio and Aeromonas.

    Summary:

    • Vibrio cholerae (O1 and non-O1) and Vibrio albensis demonstrated high sensitivity to vibriostatic O129, showing no growth even at high drug concentrations.
    • Halophilic vibrios and a portion of Aeromonas isolates showed reduced sensitivity or resistance to vibriostatic O129.
    • Aeromonas and Plesiomonas species were generally resistant to vibriostatic O129.

    Impact:

    • The differential sensitivity to vibriostatic O129 can serve as a biological characteristic for taxonomic differentiation between the genera Vibrio and Aeromonas.
    • This finding aids in the precise classification within the Vibrio genus, enhancing microbiological diagnostics and research.
    • Establishes vibriostatic O129 as a valuable tool in bacterial taxonomy and identification.

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