Related Experiment Video
Updated: Aug 23, 2025

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Comparison between Cardiac CTA and Echocardiography for Assessment of Ventricular Septal Rupture Diameter and Its
Tongfeng Chen1, Yuhao Liu1, Jing Zhang1
1People's Hospital of Zhengzhou University, Heart Center of Henan Provincial People's Hospital/Central China Fuwai Hospital/Henan Key Laboratory of Coronary Heart Disease Control/Henan Research Center for Cardiovascular Epidemiology, Zhengzhou 450003, China.
Insights
Cardiac computed tomographic angiography (CTA) offers more accurate assessment of ventricular septal rupture (VSR) diameter than echocardiography. CTA measurements correlated better with postoperative occluder size, indicating superior precision for VSR evaluation.
Area of Science:
- Cardiology
- Medical Imaging
- Interventional Cardiology
Background:
- Ventricular septal rupture (VSR) is a serious complication requiring accurate diameter assessment for treatment.
- Transcatheter occlusion is a common treatment for VSR.
- Accurate measurement of VSR diameter is crucial for successful occlusion and patient outcomes.
Purpose of the Study:
- To compare the accuracy of cardiac computed tomographic angiography (CTA) versus echocardiography in assessing ventricular septal rupture (VSR) diameter.
- To evaluate the correlation between imaging measurements and postoperative occluder size.
Main Methods:
- A total of 44 VSR patients undergoing transcatheter occlusion were randomly assigned to either a CTA or echocardiography group.
- Clinical, operative, and 30-day follow-up data were collected and analyzed.
- Correlation analysis was performed between imaging-derived diameters and postoperative occluder dimensions.
Main Results:
- Cardiac CTA demonstrated a significantly lower mean residual shunt volume compared to echocardiography (2.1 mm vs 4.2 mm, p=0.005).
- Postoperative occluder diameter showed the strongest correlation with long diameter (r=0.799, p<0.001) and mean diameter (r=0.740, p<0.001) measured by CTA.
- Echocardiography measurements did not correlate with postoperative occluder diameter.
Conclusions:
- Cardiac CTA provides a more accurate assessment of VSR diameter compared to echocardiography.
- CTA measurements are more reliable in predicting postoperative occluder fit and VSR closure success.
Objective:
This study is aimed at comparing cardiac computed tomographic angiography (CTA) with echocardiography in the assessment of ventricular septal perforation diameter.
Methods:
A total of 44 ventricular septal rupture (VSR) patients undertaking transcatheter occlusion were included and randomly divided into the CTA group and echocardiography group with a 1 : 1 ratio. Clinical data, operation-related data, and 30 d follow-up data were collected and analyzed.
Results:
Incidence of closure failure, occluder displacement, poor occluder molding, and occluder waist diameter shrinkage between the two groups were not statistically different. The mean residual shunt volume in the echocardiography group (4.2 (3.1, 5.9) mm) was significantly higher than that in the CTA group (2.1 (0, 4.0) mm) with a p value of 0.005. However, no significant differences were found in all-cause mortality and incidence of operative complications within 30 days after surgery. Within the CTA group, the correlation was strongest between postoperative occluder diameter and long diameter measured by CTA with a correlation coefficient of 0.799 and p < 0.001, followed by the correlation between postoperative occluder diameter and mean diameter measured by CTA with a correlation coefficient of 0.740 and p < 0.001. The diameter measured by echocardiography was not correlated to postoperative occlude diameter.
Conclusion:
Assessment of VSR diameter by cardiac CTA is more accurate than by echocardiography.
More Related Videos
09:57Four-Dimensional Computed Tomography-Guided Valve Sizing for Transcatheter Pulmonary Valve Replacement
Published on: January 20, 2022
09:32Time-Resolved, Dynamic Computed Tomography Angiography for Characterization of Aortic Endoleaks and Treatment Guidance via 2D-3D Fusion-Imaging
Published on: December 9, 2021
Related Concept Videos
Imaging Studies for Cardiovascular System V: CT
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for...
Acute Coronary Syndrome III: Diagnostic Studies
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion,...