Sensitive electrochemical sensor based on nickel/PDDA/reduced graphene oxide modified screen-printed carbon electrode...

Area of Science:

• Analytical Chemistry
• Electrochemistry
• Materials Science

Background:

• Nitrite determination in food is crucial for safety and quality control.
• Existing methods for nitrite analysis can be complex or lack sensitivity.
• Development of rapid, sensitive, and selective sensors is an ongoing analytical challenge.

Purpose of the Study:

• To develop a simple, rapid, and highly sensitive electrochemical sensor for nitrite determination.
• To modify a disposable screen-printed carbon electrode (SPCE) for enhanced analytical performance.
• To validate the sensor's applicability in real food samples.

Main Methods:

• Fabrication of a novel electrochemical sensor using nickel (Ni), poly(diallyldimethylammonium chloride) (PDDA), and reduced graphene oxide (rGO) on an SPCE.
• Electrochemical analysis of nitrite using cyclic voltammetry (CV) under optimized conditions.
• Characterization of sensor performance, including linear working range, limit of detection (LOD), limit of quantification (LOQ), and sensitivity.

Main Results:

• The Ni/PDDA/rGO/SPCE demonstrated a linear working range of 6 to 100 μM for nitrite.
• Achieved a low limit of detection (LOD) of 1.99 μM and limit of quantification (LOQ) of 6.6 μM.
• Exhibited excellent anti-interference capabilities and long-term stability, with high sensitivity values.

Conclusions:

• The developed disposable electrochemical sensor provides a sensitive and selective platform for rapid nitrite detection.
• The sensor successfully determined nitrite in food samples like sausages and pickled vegetables with satisfactory recovery rates.
• This Ni/PDDA/rGO/SPCE offers a promising tool for routine food safety analysis.