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Author Spotlight: Optimizing Scorpion Venom Extraction for Antivenom Production
Published on: October 6, 2023
Retrospective Evaluation of Patients With Scorpion Stings Admitted to the Pediatric Emergency Clinic
Feyat Tunç1, Süleyman Yıldız2, Mehmet Celal Devecioglu3
1Pediatrics and Child Health, Batman Training and Research Hospital, Batman, TUR.
Insights
Scorpion stings pose a significant health risk to children, often leading to severe complications. Early recognition and prompt antivenom administration are crucial for managing severe cases in pediatric patients.
Area of Science:
- Pediatric Emergency Medicine
- Toxicology
- Epidemiology
Background:
- Scorpion stings represent a considerable public health concern, particularly in pediatric populations.
- Children face heightened risks for severe cardiac, respiratory, and neurological sequelae due to lower body mass.
Purpose of the Study:
- To retrospectively analyze demographic data, clinical presentations, and treatment outcomes of pediatric scorpion sting cases.
- To identify risk factors and patterns associated with severe scorpion envenomation in children.
Main Methods:
- Retrospective analysis of 72 pediatric patients diagnosed with scorpion stings between 2013 and 2017.
- Evaluation of patient demographics, presenting complaints, clinical findings, laboratory results, and treatment interventions.
Main Results:
- The majority of pediatric patients (65.3%) resided in rural areas, with lower extremities being the most common sting site (51.4%).
- Common symptoms included pain (70.8%), edema (58.3%), and cold extremities (41.7%). While most cases were mild (71.4%), 32.9% required intensive care, and two fatalities occurred.
- Significant differences in glucose, urea, creatine, and electrolyte levels were observed between admission and discharge.
Conclusions:
- Scorpion stings remain a significant pediatric health issue, with a notable incidence of severe clinical courses.
- Effective management hinges on early diagnosis, timely antivenom therapy, and comprehensive cardiorespiratory and systemic support.
Abstract:
Introduction Scorpion sting in children is still a serious health problem today. Children are at greater risk of developing severe cardiac, respiratory, and neurological complications because of their low body weight. In this study, we retrospectively evaluated the demographical changes, complaints, clinical findings, and laboratory results of scorpion sting cases admitted to the pediatric emergency department. Materials and Methods The records of 72 patients who were followed up with the diagnosis of scorpion sting in the Dicle University Pediatric Emergency Department between 2013 and 2017 were retrospectively analyzed. Results The patients included in the study were between one and 15 years (7.64±4.04 years) and 43.1% were male, and 56.9% were female. While 65.3% of the cases lived in rural areas, 34.7% lived in the city center. The most common stung areas in the cases were the lower extremity (51.4%) and the upper extremity (34.7%). The most common complaints in the patients were 70.8% pain, 58.3% edema, 41.7% cold extremities, 23.6% sweating, 22.2% vomiting, and 12.5% excessive salivation. Of the cases, 71.4% had mild, 25.7% had moderate, and 2.9% had severe stages. Of the patients, 91.6% were given antivenom, 75.7% were given antihistamines, 74.3% were given steroids, 65.7% were given antibiotics, 64.3% were given analgesics, 44.3% were given tetanus vaccine, 2.8% were given erythrocyte suspension and 1.4% were given platelet suspension. In addition, 11.4% of the cases were given prazosin treatment. While 32.9% of the cases required intensive care, two patients died. A statistically significant difference was found between the glucose, urea, creatine, total protein, sodium, potassium, alanine aminotransferase, white blood cell count, red blood cell count, hemoglobin, hematocrit, neutrophil count values of the patients at admission and discharge. Conclusion Scorpion sting cases are still a significant health problem. The severe clinical course is more common in children. The management of patients with severe clinical forms is based on early recognition of the sting, antivenom serum administration, and cardiorespiratory and systemic support.
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