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Updated: Jun 8, 2026

Surgical Injury to the Mouse Pancreas through Ligation of the Pancreatic Duct as a Model for Endocrine and Exocrine Reprogramming and Proliferation
07:44

Surgical Injury to the Mouse Pancreas through Ligation of the Pancreatic Duct as a Model for Endocrine and Exocrine Reprogramming and Proliferation

Published on: August 7, 2015

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Regression of the ventral and dorsal pancreatic duct

Terumi Kamisawa1

  • 1Department of Internal Medicine, Tokyo Metropolitan Komagome, Hospital, Tokyo, Japan.

Journal of Hepato-Biliary-Pancreatic Sciences
|November 2, 2022
PubMed
Abstract

No abstract available in PubMed .

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Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...

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