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Updated: Aug 23, 2025

Diagonal Method to Measure Synergy Among Any Number of Drugs
Published on: June 21, 2018
Synergistic Effect of Piperine and its Derivatives: A Comprehensive Review
Neha Saini1, Bhawna Chopra1, Ashwani K Dhingra1
1Department of Pharmacy, Guru Gobind Singh College of Pharmacy, Yamuna Nagar-135001, Haryana, India.
Abstract:
Piperine is a fascinating substance since it can be used as a biomarker in combination with other bioactive compounds or their analogues, as well as therapeutic molecules used for the healing of a variety of diseases. It displays a plentiful therapeutic potential and various health benefits when administered alone or in combination with several other drugs and/or phytochemicals. It has also been used to enhance the pharmacokinetic profile of many nutraceutical compounds like curcumin, resveratrol, quercetin, beta-carotene, barbiturates, propranolol, metformin, theophylline etc. The present review discloses the synergistic effect of piperine and its derivatives, clinical studies, and patent studies of piperine.
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